Pseudomonas aeruginosa eradication: Finally moving the needle?
نویسندگان
چکیده
منابع مشابه
Eradication of Pseudomonas aeruginosa in cystic fibrosis.
We read with interest the recently published article by TACCETTI et al. [1] in the European Respiratory Journal and the accompanying editorial by JONES [2]. TACETTI et al. [1] report on their experience with early eradication therapy against Pseudomonas aeruginosa (PA) in cystic fibrosis (CF), concluding that this treatment exerts a number of beneficial effects and is also cost-effective. Howev...
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Chronic pulmonary infection with Pseudomonas aeruginosa is responsible for most of the morbidity and mortality in cystic fibrosis (CF). Once established as a biofilm, chronic P. aeruginosa infection caused by the mucoid phenotype cannot be eradicated. However, a period of intermittent colonization with P. aeruginosa precedes the establishment of the chronic infection. This window of opportunity...
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BACKGROUND No prospective study has assessed eradication treatment of early Pseudomonas aeruginosa colonisation in bronchiectasis not due to cystic fibrosis (CF). OBJECTIVES To evaluate the efficacy of 3 months of nebulised tobramycin after a short course of intravenous antibiotics in the eradication of P. aeruginosa and its clinical consequences in non- CF bronchiectasis following initial P....
متن کاملEradication Therapy against Pseudomonas aeruginosa in Non-Cystic Fibrosis Bronchiectasis
Background: No prospective study has assessed eradication treatment of early Pseudomonas aeruginosa colonisation in bronchiectasis not due to cystic fibrosis (CF). Objectives: To evaluate the efficacy of 3 months of nebulised tobramycin after a short course of intravenous antibiotics in the eradication of P. aeruginosa and its clinical consequences in nonCF bronchiectasis following initial P. a...
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Biofilms are defined as aggregation of single cell microorganisms and associated with over 80% of all the microbial infections. Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen capable of leading to various infections in immunocompromised people. Recent studies showed that norspermidine, a kind of polyamine, prevented and disrupted biofilm formation by some Gram-negative bacteri...
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ژورنال
عنوان ژورنال: Journal of Cystic Fibrosis
سال: 2017
ISSN: 1569-1993
DOI: 10.1016/j.jcf.2017.04.001